分析抗体库并发现新的v基因
igdiscover的Python项目详细描述
igdiscover
igdiscover分析抗体库,并从高通量测序读数中发现新的v基因。 支持重链、kappa和lambda轻链(以发现vh、vk和vl基因)。
igdiscover是Gunilla Karlsson Hedestam group 在Department of Microbiology, Tumor and Cell Biology和Karolinska Institutet处, 瑞典和{a7}设施 在瑞典的Science for Life Laboratory (SciLifeLab)。
如果您使用igdiscover,请引用:
Corcoran, Martin M. and Phad, Ganesh E. and Bernat, Néstor Vázquez and Stahl-Hennig, Christiane and Sumida, Noriyuki and Persson, Mats A.A. and Martin, Marcel and Karlsson Hedestam, Gunilla B.Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity.Nature Communications 7:13642 (2016)