Python:如果。。。else False语句（布尔值）

Question

Transitions between A <-> G and C <-> T
Transversions between A <-> C and G <-> T

Assignment:

• Write a function transition that takes two nucleotides. The function must return a Boolean value that indicates whether or not replacing the first nucleotide by the second nucleotide leads to a transition.

问题：我认为函数无法识别or后面的语句。 代码在某些情况下不起作用，例如：transition('A', 'G')为True，而对于我的代码，他给出False

• Write a function ratio that takes two DNA sequences s1 and s2
  The function may assume that both sequences have the same length (the function does not need to check this explicitly). The function must return the transition/transversion ratio R(s 1 ,s 2 )∈R of the two given sequences as a floating point number. In case there are no transversions between the two sequences, R(s 1 ,s 2 )=0 by definition.

问题：代码不起作用

def transition(letter1, letter2):        
    """
    >>> transition('G', 'A')
    True
    >>> transition('t', 'g')
    False
    >>> transition('C', 'c')
    False
    """    
    return True if letter1.lower() == 'gt' and letter2.lower() == 'ac' or letter1.lower() == 'ac' and letter2.lower() == 'gt' else False


def transversion(letter1, letter2):
    """
    >>> transversion('G', 'A')
    False
    >>> transversion('t', 'g')
    True
    >>> transversion('C', 'c')
    False
    """
    return True if letter1.lower() == 'ct' and letter2.lower() == 'ag' or  letter1.lower() == 'ag' and letter2.lower() == 'ct' else False


def ratio(seq1, seq2):
    """
    >>> ratio('ATTAGCATTATCATC', 'AAATAGGATATATGG')
    0.2222222222222222
    >>> seq1 = 'GCAACGCACAACGAAAACCCTTAGGGACTGGATTATTTCGTGATCGTTGTAGTTATTGGAAGTACGGGCATCAACCCAGTT'
    >>> seq2 = 'ttatctgacaaagaaagccgtcaacggctggataatttcgcgatcgtgctggttactggcggtacgagtgttcctttgggt'
    >>> ratio(seq1, seq2)   
    1.2142857142857142
    """
    count = 0
    tel = 0

    for i in range(len(seq1)):
        if transition(seq1[i], seq2[i]):
            count += 1

    for i in range(len(seq1)):
        if transversion(seq1[i], seq2[i]):
            tel += 1

    if tel != 0:
        return float(count / tel)
    else:
        return 0 

if __name__ == '__main__':
    import doctest
    doctest.testmod()

Answer 1

我认为相同碱基的^{}或^{}必须返回False
（即transition('A','A')==False）

您可以简化使用简单的命名谓词：https://repl.it/N4TC/4

def transition(nucleobase1, nucleobase2):        
   """ True if both are different and are purine
   """
   return (not isEqual(nucleobase1, nucleobase2) and
           isPurine(nucleobase1) and 
           isPurine(nucleobase2))

def transversion(nucleobase1, nucleobase2):        
   """ True if both are different and not transition
   """
   return (not isEqual(nucleobase1, nucleobase2) and
           not transition(nucleobase1, nucleobase2))

其他谓词：

### nucleobase Predicat    

def isAdenine(nucleobase):
    """ True if adenine (A)
    """
    return nucleobase.lower()=='a'

def isCytosine(nucleobase):
    """ True if cytosine (C)
    """
    return nucleobase.lower()=='c'

def isGuanine(nucleobase):
    """ True if guanine (G)
    """
    return nucleobase.lower()=='g'

def isThymine(nucleobase):
    """ True if thymine (T)    
    """
    return nucleobase.lower()=='t'

def isPurine(nucleobase):
    """ True if adenine (A) or guanine (G)
    """
    return isAdenine(nucleobase) or isGuanine(nucleobase)

def isPyrimidine(nucleobase):
    """ True if cytosine (C) or thymine (T)
    """
    return isCytosine(nucleobase) or isThymine(nucleobase)

def isEqual(nucleobase1, nucleobase2):
    """ Equal ignore case
    """
    return nucleobase1.lower()==nucleobase2.lower()      

Answer 2

把线改成这样

return True if letter1.lower() == 'gt' and letter2.lower() == 'ac' or letter1.lower() == 'ac' and letter2.lower() == 'gt' else False

签署人：

return (letter1.lower() == 'gt' and letter2.lower() == 'ac' or letter1.lower() == 'ac' and letter2.lower() == 'gt') 

Answer 3

一般来说，如果有多个条件，可以先将它们赋给变量。可能不是您想要的答案，但可能可以帮助您编写更易于阅读的代码。

像这样：

letter1 = "GT"
letter2 = "AC"

def transition(letter1, letter2):

    cond1 = (letter1.lower() == 'gt')
    cond2 = (letter2.lower() == 'ac')
    cond3 = (letter1.lower() == 'ac')
    cond4 = (letter2.lower() == 'gt')

    if (cond1 and cond2) or (cond3 and cond4):
        return True
    else:
        return False

transition(letter1,letter2)