最大连续字数

Question

< >考虑以下薰衣草DNA序列：

GCTAAATTTGTTCAGCCAGATGTAGGCTTACAAATCAAGCTGTCCGCTCGGCACGGCCTACACACGTCGTGTAACTACAACAGCTAGTTAATCTGGATATCACCATGACCGAATCATAGATTTCGCCTTAAGGAGCTTTACCATGGCTTGGGATCCAATACTAAGGGCTCGACCTAGGCGAATGAGTTTCAGGTTGGCAATCAGCAACGCTCGCCATCCGGACGACGGCTTACAGTTAGTAGCATAGTACGCGATTTTCGGGAAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGAATGTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCCCGTCAACTCATTCACACCGCATCCTTTCCTGCCACTGTAACTAGTCGACTGGGGAACCTCATCATCCATACTCTCCCACATTATGCCTCCCAACCTTGTTAAGCGTGGCATGCTTGGGATTGCATTGATGCTTCTTGGAGAGGACGCTTTCGTTTTGGAGATTACAGGGATCCAATTTTATCATCGGTTCGACTCCCGTAACGACTTAGCAGTAAGGGTGCTAGTTCCTGGTTAGAATCTTAATAAATCACGTCGCTTGGAGCAAGACAAAGATCGTCGTAATGCCAAGTGCACGACCACCTTCAGACTTGCAGGACCCGTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTTTTTTTCTCGATAGCTATGCGGTTCAATACAATCTTAACGCAATGCAGCGATGTGGTTTCGTACACTTAGCATAAAACCCCCCACATTAAATCGATGTACCCGCCCTCTTAGACGCCAATTTCAATGCCGAACCTCCGGCGGGTATCTCTGCACTAGGAGAAGTAGCACGTCGCTGTAGCGAACTCCTATCGTGAGATAATTTGTAGAGCTGCTCTTATAATACAATAGCTCAGATGGATTATTCCATGGACATCCCCGTGCGTTGTTTCGAGGATGGTAGGTGGAAATTTTGCCAGACCTCTAGTCTTAAACATGGTTGACGTTATAGGCGCTATCTCTTGCGTCTGGAAGTGTTAATCCGTGAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAACACGCAACTCTGGAGGAGGGCACTGCACTGCAAACTTGCGTAATATCCTTCACCCACACTTGCCTGGCCTCCTTGCTTAAAGCTCTGGCGATGCGATTTTTCGGCCCAGTAGCTGAATAGGTCATGAAATGGGCACCGAACTGGAAAGACCCATATATTCGATACTCACAACTTAATGATAGCGCGATTAAGAGCGACACCAAAAACCAAATTACGTTCACGAACCTTTGAGAGTCAAGGAGACTTAGACCGAATTGAATGATCACTGATGCGCCCGCTGATACTGAGCCTCACCATTAATCGCCGACCAATACGGCGTGTACCGGGCGCGGCCTTGCCGCATAACGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATATCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTACACAGCCCCGTCCTCATTGCTAAGTGCACTGGCAACTGGACCTAAAGATTTTTCGAGTATGGCCCTCGAATCAAGCGCCCACCCAGAAACCTACGAGCCAGTAACCCCAGTAAACAAGCATTAGTGCTATATGCTTGCTGCCCACTAGGACCCTTATGGTTCATACCAGGGTGACGTGTCTTGCGGGCCAAGGATGAACCAGAAGCAAGATCCTTAGATGGACGACTGTCTCATTGCTTAAACTCCACATACCAAAGGGCGCGGTAAACGATAGTTTTAGGTAATGTTAGTCGGATGGTTGTCTGCAGCTACCAATACAGCCTGGCACCCAGGGTCTGAACAATAACGCGTGAGAGCAGCTCTCCCGCGTGTGGTGGATTTGCCGTCTATGAAATTGAGGCTCTTGCAACTATTCGCACTCGGAATGCCCTCATATCTGGTGCCTAGCGGCCTTTGCCCCGTGCCGGTAGGACTAAACTCTACGGATCGTTGACGGATCTCGATGTGGAAGATGGTTATGAAAGATAACAACGCGTGTGCTAATTGATTTAGACAAGTATTGCGGCAGTAAAAGATAATCGGCTGCAGAGTTACGAAAGACTTCCATGCATGGATTCCATTCCTTCTAGTATAGGACCCACTCTGAATACACGTCTTGCGGGCCGATCATCTCCACCGCTGCGGAAGAAAGCAATTAAGAATCTATGCTCATTAAGAGTGCGACTATAATGCGGATCTTACAGTGCTAATGATCAGGACGTCGTCCAAGCAGGCTGCATGCCGAATTTAGCTTACGTCAGGATCAGGCGTTATAGCCTGGGAATCGGACTATGAGGACGCCACGACCTCTGGGAGAAAGCTATATACATTGAGGATCGCGCCATCTTTATGAGACTCAAATGAATCTAGATAGGTAGCATTGCGGACTTGAGTTAGCACATCGGTATTGGAAGGTGAGGGTCCTGCCGCTCGTTCTATGTTCGGTTTATAGTATACAAATAGGTCATCCCGAACGTTGAAGTTAAACTCATGACACGTTGTCGTAATGAAACGGGCCTGTTATTAGGGATACAGACAAAAGGCACAAGCTGGCTTGCACATTAAGGCGCACTAGAGATCCTCACAACCGTTGCCCGCACGGAGGTCGTGTCTAACAGACAGTGAACCAGCCGTATTGGGGTGGATGACCTGAGCTTCTTGGGGCCTGTTGTACACCGCGTGTGGTTCAACTGGTACACATACTACGAATATTCGAAATCATTGTACTGTGCTCTTCGGTGCTACTGACTGTGAGCGAATGCATCCCAATCCCAAACAATGCTTGTGGTAGGAGAATTGAAACTCTCGAAGCCTGGCCCAATGTCATCTACTTTTAACATGTCGGGCCAGGAGTTACGGGCATTGCTTACTTACTTTGCCCCCTTACACCACAGCAGCGCGATTCTTGTTGTAGTAGATTTTATACGACTCGCGAATTAAATGGAACTTGTCTGTCCCATATCGATCGTGTCCATCGTAAGATGAGATTGTAGGAGCATTCGGAAGTCTATGCGGCCCAGGGACTACTACGTTAAATCTGGTCAGACGTGGTTTACAAGGCGTCCCGATCTTCTCAGAACATATGGGAAAGCACTACCGTTCCTTCACGCATACAGTTGTTCGTGCCGAACGAGTAAGCTTGCGACCAGCCCACCCGCTAGGGCTATGCAGCGGGTCATGGCTGGCGCCATACTGTGCGGACAACCCACGCTCTGGCAGAAAGCGTCTTGTGTTTTGTAGTAGCTCCAACGGTTAGACCTTCGATATCTATTCAGAGCGCGAGCGACCACTATTAGACGGCATGTAAACAATGTGTATTTGTTCGGCCCAACCGGTATATGGGTAAGACCGCGAAGGGCCTGCGCGAATACCAGCGTCCAAAAATTCCTCACCCGAGATATGCGGTTAGTACCCCTTGGGTAACGGTCCGCTACGGGTAGCGACGCGAGCCGGCCGCATCGGTTGGAGCCGAGTTGTCGGGCAGGCGAGTAACGTGTGCAATTTGATGGGCCCAAGCCTCCGGCACTATCCACCTCATACATCGACAAAAGCACCAAATATGGGGAAAAGCTGAGCGTCGATATGTACATCTACCCAGGAACCGGCCCGAACATTAGGCGGACGTGAATTTCCGACCTAGGTTCGGCTACATTTCTACGATCCAAGCACACGTGAAGGAGGAGGGGTGTTCCGACCGTAAATGAACGAGGTGCGCAGTGACCCGATGGCGTTTAGCGGATAGCCTTCCTATGCCGGCCTATGCTGTATGGTAGTTGGTTGGTGCCTCCAGAGCCACTGCACCCAATCATAGGGTCTACAGCAGCGTACTTATAAAATTGTACGGGTGACCCATATCCATTACGGGTTGCGACCAGTATAGGAGAGTATAACTGCGTGAACTAATGCGTTATGACGCTTCAGAGTTTGCTCGGGCCCGAGTTCTAGGGCTATAATGTGTTAGGGCGCAAGTATGCCAAGCTAAGATGTGGCGTGCACACTAGGAGTTGTGTTCCTCTGCAAGCAGACACGAGCACTCTGGCAGTAGTTTGACCACACCCGGGTATCACTGCTACTCCATTTCGAACAAGCTATTGGAGCGGACAAAATATGCTACTCAAGAGCATTAGTTATAGGTCTACGAGACAGAAGCAGTTACTGAGTCTGAATATTCGATATAAGTAGGCATGGAGGCGGAGCAAAACAACGTCTGCGATCAATCGTGTTGATGACGTATGGCGACTGGAAGGTAAGGACTATGGCCGGACGGAATGATTCATGTTCTGTTCAAAGCTATATTTCGAAGGGGTATATTAGCGGTCCTACACTTGGTTAGCACCCTCCCCCCTCTGGATCCTGCACTAATTCGAGCTGGCCTCCATCGGTATCAGTCCGGAAGCTCCACTCTCTATCGTAGTCCTAATCAACAGGGTGCCAGTTTGCTCACGTGGAAGTTTGAGGCCCTTTGTGCTCCATAGCCAATCACTAACCATGCACGCGCGACCCACTCTACGTCCAGATCGGCTATAATAGTTGCGCCCGGGACTGGCAGAGTAGACATGTAAGCTAGATAGAGCCCCGACATCGGCCAAGAGATCCTACGCTGCTTCCAGATAATGAGAGACATTCTAGCATTAGACATGCAAGTCGGCAGGGACTCCCCTTATCTAGTAATTTCGATGAATTGGTTTTTCGGCTAGCATCTAGTCTAGTCTAGTCTAGTCTAGTCTAGTCTAGTCTAGTCTAGTCTAGTCTAGTCTAGACCATGCCGACCTCATCATAGAAGGAATGCTCTAAACTTAGAGTGCTACTAGGAAAACTATTAATCAATGATCGTCCTGCTTACATAGCTGGACGGCGAAAGTTCTTATACTGCGGAGGTTGCTGACGTAGAGTGCGCTGGGTACAGCGGATAAGTTGATCAGGGTGGGGATAGGGTGGCTCACCGTTTATACTCATATAGATTCCTGGCGTCGACGCTGTGACAGGGTCGAGATCGAGGGGGAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGATCAGCGGAGCGGAGGGAAAATTATCACCAGAGGGTAGGGGCTCGCGACATTCTATTCAATGCATTTCAAGCTACTTACGTATTTCGGCACAGTGACTACTGCCTGCGCGGCAGCCGTAAGGTTTCCCGTCAATAGGTGGCACGTATCATTGATGAAAGTGTCAGCTAATCATTCAGGCCTTA

这本字典呢

sqc_large_dictionary = ["AGATC","TTTTTTCT","AATG","TCTAG","GATA","TATC","GAAA","TCTG"]

这就是我们必须在Lavender的DNA序列中寻找的单词

问题是，例如，我使用re和collections创建了一个检测所有AATG的算法（66）。但是规范告诉我，我应该只计算最长的连续序列，在本例中是43，因为其他的序列都是浇水的，但是有43个AATG，一个在另一个后面，这是我应该取的数字。我如何实现这一点

Answer 1

如果你能将序列按元素分割，得到如下结果：

lst = ['ATG','ATG','ATG','ATG','ATG','asd','ATG']

您可以使用：

from itertools import groupby
for a, g in groupby(lst):
    print(a, len(list(g)))

ATG 5
asd 1
ATG 1

Answer 2

你可以得到所有的序列，然后分组，最后得到最大值

>>> sequences = re.findall(str.join('|',sqc_large_dictionary),l)
>>> groups = [(k,len(list(grp))) for k,grp in itertools.groupby(sequences)]
>>> max(groups, key=lambda x:x[1])
('GAAA', 47)

要获得每个序列类型的最大值，可以执行以下操作：

>>> res = defaultdict(int)
>>> for k,v in groups:
...     res[k] = max(res[k], v)
... 
>>> res
defaultdict(<class 'int'>, {'TCTG': 41, 'GATA': 27, 'AATG': 42, 'GAAA': 47, 'TATC': 19, 'AGATC': 23, 'TTTTTTCT': 33, 'TCTAG': 12})